Epiretinal Membrane Surgery After Retinal Detachment Repair: Visual Acuity Outcomes and OCT Analysis

Epiretinal Membrane Surgery After Retinal Detachment Repair Visual Acuity Outcomes and OCT Analysis

Epiretinal membrane (ERM) formation commonly occurs after primary rhegmatogenous retinal detachment (RD) repair with a variable incidence of 6.1 to 12.8%. It is thought to be secondary to the release of retinal pigment epithelium (RPE) cells from the retinal break and subsequent proliferation on the retinal surface. The disruption of the retinal surface contour may result in decreased visual acuity or development of metamorphopsia. Studies on optical coherence tomography (OCT) features as predictors of VA outcomes in eyes with secondary ERM after RD repair are limited to date. 


In this retrospective, consecutive case series, Soares et al identified 53 eyes of 53 patients that underwent membrane peeling (MP) with internal limiting membrane (ILM) removal after primary RD repair with pars plana vitrectomy with or without scleral buckle. The patient’s VA improved from 20/200 to 20/56 within 6 months after MP. Eyes with macula-on RD had better VA at 6 months (20/39). MP occurring 180 days or less from RD repair and inner segment/outer segment (IS/OS) loss on OCT were associated with worse visual outcomes. In addition, RD repair with pars plana vitrectomy/ scleral buckle prior to MP was associated with worse VA at 6 months after MP.


In summary, eyes undergoing MP after RD repair had improved visual acuity overall, regardless of ERM stage and macula status at time of RD. However, eyes with IS/OS disruption pre-MP were associated with worse visual acuity outcomes after MP compared to eyes without this finding on OCT.  

Details
  • Overview

    August 2021: VBS Literature Update

    Soares RR, Mahmoudzadeh R, Salabati M, et al. Epiretinal membrane surgery after retinal detachment repair: Visual acuity outcomes and OCT analysis. Ophthalmol Retina. 2021:S2468-6530(21)00103-2.

    Abstracted by Dan Su, MD

  • Learning Objectives

    Upon completion of this activity, the participant should be able to:

    • Identify clinical features associated with worse visual acuity outcomes after membrane peeling in eyes with prior retinal detachment repair
    • Use OCT features to prognosticate visual acuity outcomes when counseling this patient population
    • Participation Method

      In order to obtain credit, proceed through the program, complete the post-test, evaluation and submit for credit.

    • Faculty and Disclosures

      Daniel Su, MD

      Daniel Su, MD

      Retina-Vitreous Associates Medical Group
      Los Angeles, CA


      DISCLOSURE POLICY
      It is the policy of Evolve that faculty and other individuals who are in the position to control the content of this activity disclose any real or apparent conflicts of interest relating to the topics of this educational activity. Evolve has full policies in place that will identify and mitigate all conflicts of interest prior to this educational activity.

      The following faculty/staff members have the following financial relationships with commercial interests:

      Daniel Su, MD,  has no financial relationships with ineligible companies.

      The Evolve staff and planners have no financial relationships with commercial interests.
      Nisha Mukherjee, MD, peer reviewer, has no financial relationships with commercial interests.

    • Disclaimer

      OFF-LABEL STATEMENT
      This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The opinions expressed in the educational activity are those of the faculty. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

      DISCLAIMER
      The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of Evolve. 

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