The Art of Submental Contouring: Novel Treatment Approaches for Total Facial Rejuvenation
18
American Society for Dermatologic Surgery (ASDS). 2015 ASDS Consumer Survey on Cosmetic Dermatologic Procedures. April 2015.
Allergan, Data on File, Submental Fullness Survey, April 2016.
Key DJ. Comprehensive thermoregulation for the purpose of skin tightening using a novel radiofrequency treatment device: a preliminary report. J Drugs Dermatol. 2014 Feb;13(2):185-9.
Park JH, Kim JI, Park HJ, Kim WS. Evaluation of safety and efficacy of noninvasive radiofrequency technology for submental rejuvenation. Lasers Med Sci. 2016 Nov;31(8):1599-1605.
McDiarmid J, Ruiz JB, Lee D, Lippert S, Hartisch C, Havlickova B. Results from a pooled analysis of two European, randomized, placebo-controlled, phase 3 studies of ATX-101 for the pharmacologic reduction of excess submental fat. Aesthetic Plast Surg. 2014 Oct;38(5):849-60.
Jones DH, Carruthers J, Joseph JH, Callender VD, Walker P, Lee DR, Subramanian M, Lizzul PF, Gross TM, Beddingfield FC 3rd. REFINE-1, a Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial With ATX-101, an Injectable Drug for Submental Fat Reduction. Dermatol Surg. 2016 Jan;42(1):38-49.
Humphrey S1, Sykes J2, Kantor J3, Bertucci V4, Walker P5, Lee DR5, Lizzul PF5, Gross TM5, Beddingfield FC 3rd6. ATX-101 for reduction of submental fat: A phase III randomized controlled trial. J Am Acad Dermatol. 2016 Oct;75(4):788-797.e7. doi: 10.1016/j. jaad.2016.04.028. Epub 2016 Jul 16.
Kilmer SL, Burns AJ, Zelickson BD. Safety and efficacy of cryolipolysis for non-invasive reduction of submental fat. Lasers Surg Med. 2016;48:3-13.
Shridharani SM. Early Experience in 100 Consecutive Patients With Injection Adipocytolysis for Neck Contouring With ATX-101 (Deoxycholic Acid). Dermatol Surg. 2017 Apr 12. [Epub ahead of print]
Dover JS, Kenkel JM, Carruthers A, Lizzul PF, Gross TM, Subramanian M, Beddingfield FC 3rd. Management of Patient Experience With ATX-101 (Deoxycholic Acid Injection) for Reduction of Submental Fat. Dermatol Surg. 2016 Nov;42 Suppl 1:S288-S299.
DeFatta R, Ducic Y. Liposuction of the face and neck. Operative Techniques in Otolaryngology-Head and Neck Surger. 2007 18(3): 261-266
Schlessinger J, Weiss SR, Jewell M, Narurkar V, Weinkle S, Gold MH, Bazerkanian E. Perceptions and practices in submental fat treatment: a survey of physicians and patients. Skinmed. 2013 Jan-Feb;11(1):27-31.
Mulholland RS. Nonexcisional, minimally invasive rejuvenation of the neck. Clin Plast Surg. 2014 Jan;41(1):11-31. doi: 10.1016/j. cps.2013.09.002.
Thomas WW, Bloom JD. Neck Contouring and Treatment of Submental Adiposity. J Drugs Dermatol. 2017 Jan 1;16(1):54-57.
Huettner F, Vasconez LO, de la Torre JI. Neck rejuvenation--anatomy and clinical correlation. Facial Plast Surg. 2012 Feb;28(1):40-51.
Hatef DA, Koshy JC, Sandoval SE, Echo AP, Izaddoost SA, Hollier LH. The submental fat compartment of the neck. Semin Plast Surg. 2009 Nov;23(4):288-91.
Keramidas E, Rodopoulou S. Radiofrequency-assisted liposuction for neck and lower face adipodermal remodeling and contouring. Plast Reconstr Surg Glob Open. 2016;4:e850.
Orringer JS, Ritte L, Baker D, Voorhees JJ, et al. Molecular mechanisms of nonablative fractionated laser resurfacing. Br J Dermatol. 2010 Oct;163(4):757–68.
Overview
This continuing medical education (CME) activity captures content from a roundtable discussion held in March 2017. This certified CME activity is designed for dermatologists and cosmetic surgeons. Balanced facial proportions reflected in ancient and classical art have not changed significantly over millennia, and they guide aesthetic physicians today. While fillers and neurotoxins can be used to remodel the mid-face non-invasively, the effects of chin dimensions and submental fullness have been difficult to modify without invasive surgical measures. Furthermore, in keeping with trends that focus on holistic approaches to aesthetic treatment, cosmetic surgeons are interested in treating submental fat within a regimen that also includes injectables and device-based interventions for pan-facial rejuvenation.This continuing medical education activity is supported through an educational grant from Allergan plc. Learning Objectives
Upon completion of this activity, the participant should be able to:
• Discuss ideal proportions of facial anatomy and the affects of submental fullness on the individual’s appearance.
• Articulate the method of action of deoxycholic acid and identify its role in the management of submental fat.
• Identify ideal treatment parameters for deoxycholic acid injection that optimize patient comfort and long-term outcomes.
• Determine optimal strategies for use of deoxycholic acid along with other interventions that target submental fullness.
• Describe effective strategies that incorporate targeted treatment of the submentum into a pan-facial rejuvenation strategy.
Accreditation
ACCREDITATION STATEMENT
Evolve Medical Education LLC is accredited by the ACCME to provide continuing medical education for physicians.
AMA CREDIT DESIGNATION STATEMENT
Evolve Medical Education LLC designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Faculty and Disclosures
DISCLOSURE POLICY
It is the policy of Evolve that faculty and other individuals who are in the position to control the content of this activity disclose any real or apparent conflicts of interest relating to the topics of this educational activity. Evolve has full policies in place that will identify and mitigate all conflicts of interest prior to this educational activity.DISCLOSURE POLICY STATEMENT
It is the policy of Evolve Medical Education LLC that faculty and other individuals who are in the position to control the content of this activity disclose any real or apparent conflict of interests relating to the topics of this educational activity. Evolve Medical Education LLC has full policies in place that will identify and resolve all conflicts of interest prior to this educational activity.
The following faculty members have the following financial relationships with commercial interests:
Steven Dayan, MD has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant/Advisory Board/Speaker’s Bureau: Allergan plc.; Kythera Biopharmaceuticals; L'Oreal; Medicis Pharmaceutical Corporation; Merz Aesthetics; and Sente.
Mathew Avram, MD has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant/Advisory Board/Speaker’s Bureau: Cytrellis Biosystems, Inc.; Merz Aesthetics; Sciton, Inc.; and ZELTIQ Aesthetics Inc. Grant/Research Support: Allergan plc; Cutera, Inc.; Invasix Ltd.; and ZELTIQ Aesthetics Inc. Stock/Ownership: Cytrellis Biosystems, Inc.; and Invasix Ltd.
Deborah Sherman, MD has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant/Advisory Board/Speaker’s Bureau: Allergan plc; Galderma USA; and Obagi Medical Products.
Sachin Shridharani, MD has had no financial agreements or affiliations during the past year.
EDITORIAL SUPPORT DISCLOSURES
Cheryl Cavanaugh, MS, Evolve Medical Education LLC, and Anthony Rossi, MD, Peer Reviewer, have no real or apparent conflicts of interest to report.
Disclaimer
OFF-LABEL STATEMENT
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by FDA. The opinions expressed in the educational activity are those of the faculty. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings.
DISCLAIMER
The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of Evolve Medical Education LLC and Allergan Inc.
Distributed with: Modern Aesthetics®
System Requirements
- Supported Browsers (2 most recent versions):
- Google Chrome for Windows, Mac OS, iOS, and Android
- Apple Safari for Mac OS and iOS
- Mozilla Firefox for Windows, Mac OS, iOS, and Android
- Microsoft Edge for Windows
- Recommended Internet Speed: 5Mbps+
Publication Dates
Expiration Date:
Ready to Claim Your Credits?
You have attempts to pass this post-test. Take your time and review carefully before submitting.
Good luck!

