Innovate Retina: Challenges of Bringing New Treatments to the Clinic

Innovate Retina Challenges of Bringing New Treatments to the Clinic
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  • Overview

    Innovate – Retina, The Stanford Innovation Summit series will take place virtually over the course of three virtual meetings. The summit focuses exclusively on game-changing innovations in medical and surgical retina, including current management of age-related macular degeneration (AMD) and diabetic retinopathy, ocular imaging, gene therapy, ocular inflammation, surgical technologies, ocular oncology and the latest advances in retinal pharmacotherapy. This webinar is captured from the second virtual meeting. 

    Supported by educational grants from Alcon Vision, Apellis, Carl Zeiss Meditec, Genentech, a member of the Roche Group. REGENXBIO and Regeneron Pharmaceuticals.

  • Learning Objectives

    Upon completion of this activity, the participant should be able to:

    • Identify current management of common retinal vascular diseases including wet AMD, diabetic macular edema, and diabetic retinopathy
    • Discuss the efficacy, safety and treatment regimens of current anti-VEGF agents in wet AMD, diabetic macular edema, and diabetic retinopathy including long acting formulations
    • Describe the innovation process in the academic and private practice settings
    • Examine the latest clinical data on emerging pharmacotherapeutics in retina within the context of innovation
    • Evaluate key gene therapy trials for macular and inherited retinal diseases and develop strategies for managing inflammation in these patients
    • Accreditation

      ACCREDITATION AND DESIGNATION

      This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Evolve Medical Education LLC and iVista Medical Education. Evolve Medical Education LLC is accredited by the ACCME to provide continuing medical education for physicians.

      Evolve Medical Education LLC designates this enduring material for a maximum of 3.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    • Participation Method

      In order to obtain credit, proceed through the program, complete the post-test, evaluation and submit for credit.

    • Faculty and Disclosures

      DISCLOSURE POLICY
      It is the policy of Evolve that faculty and other individuals who are in the position to control the content of this activity disclose any real or apparent conflicts of interest relating to the topics of this educational activity. Evolve has full policies in place that will identify and mitigate all conflicts of interest prior to this educational activity.

      DISCLOSURE POLICY
      It is the policy of Evolve that faculty and other individuals who are in the position to control the content of this activity disclose any real or apparent conflicts of interest relating to the topics of this educational activity. Evolve has full policies in place that will identify and mitigate all conflicts of interest prior to this educational activity.

      The following faculty/staff members have the following financial relationships with commercial interests:

      Robert Bhisitkul, MD, PhD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: RIBOMIC, Rezolute, Unity Bio, VisgenX. Grant/Research Support: Genentech, NGM Bio, RegenXBio. Stock/Shareholder and Patent: Oculinea.

      David Brown, MD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Adverum, Alexion, Annexon Biosciences, Apellis, Bayer, Boehringer Ingelheim, Celltrion, ChengduKanhong Biotechnology Co., Clearside Biomedical, Dark Horse Consulting, Horizon Therapeutics, Jefferies, Kodiak, Laboratoires THEA, Lineage, Novartis, Ocular Therapeutix, OPTOS, Regeneron Pharmaceuticals, Retinai Medical, Senju, Stealth, Verseon, and Wedbush. Grant/Research Support: Adverum, Aldeyra, Apellis, Bayer, BIRC, Boehringer Ingelheim, Clearside Biomedical, Cleveland Clinic Foundation,  F. Hoffmann – La Roche Limited, Gyroscope, Ionis, Iveris, Kodiak, Lowy Medical Research Institute, Lumithera, Nanoscope, NEI/NIH, NGM, Novartis, OIRRC, OPTOS, Oxurion, Regeneron, REGENXBIO, SanChunDang Pharm., Santen, and Senju Pharmaceutical.

      Margaret Chang, MD, MS, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Genentech, and RegnxBio. Grant/Research Support: Allergan, Genentech, Mylan, Novartis, NGM, Opthea, Ophthokol, and Regeneron Pharmaceuticals.

      Janet Davis, MD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: 4DMT, and Kodiak Biosciences. Grant/Research Support: NIH-JHU.

      Diana Do, MD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Boehringer Ingelheim, Kodiak Sciences, Mallinckrodt, Novartis, and Regeneron Pharmaceuticals.  Grant/Research Support: Boehringer Ingelheim, Novartis and Regeneron Pharmaceuticals. Stock/Shareholder: Kodiak Sciences.

      David Eichenbaum, MD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Alimera, Allegro, Allergan, Apellis, Bausch & Lomb Clearside, Eyepoint, Genentech, Gyroscope, IvericBio, KKR, Kodiak, Novartis, Notal Vision, RecensMedical, Regeneron, and RegenxBio. Grant/Research Support: Alkahest, Alimera, Allergan, Chegdu, Clearside, Gemini, Genentech, Gyroscope, Ionis, IvericBio, Kodiak, Mylan, NGM, Novartis, Ophthotech. Opthea, Recens Medical, and RegenxBio. Speaker’s Bureau: Allergan, Apellis, DORC, EyePoint, Genentech, and Novartis. Stock/Shareholder: Hemera Biosciences, US Retina, Boston Image Reading Center, Clearside, Network Eye.

      Jeffrey Heier, MD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: 4DMT, Abpro, Adverum, Aerie, Affamed, Allegro, Allergan, Allgenesis, Annexon, Apellis, Aprea, Asclepix, Aviceda, BVT, DTx, Eloxx, Galimedix, Genentech/Roche, Graybug, Gyroscope, Horizon Therapeutics, lveric, Kanghong, Lensgen, NGM, Novartis, Ocular Therapeutix, Oriole, Oxurion, Palatin, Regeneron, Regenxbio, Roche, Santen, Scifluor, Stealth Biotherapeutics, Surrozen, Thea, Verseon, Vinci. Grant/Research Support: Apellis, Asclepix, Bayer, Genentech/Roche, Gyroscope, Hemera, lveric, Kanghong, Kodiak, NGM, Notal Vision, Novartis, Regeneron, Regenxbio, and Stealth. Stock/Shareholder: Adverum, Aldeyra, Allegro, Aviceda, Digital Surgery Systems, DTx Pharma, jCyte, Ocular Therapeutix, and Vinci.

      Peter Kaiser, MD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Aerie, Allegro, Allergan, Allgenesis, Alzheon, Annexon Biosciences, AsclepiX, Aviceda, Bayer, Bausch and Lomb, Biogen Idec, Bionic Vision Technologies, Boerenger Ingelheim, Carl Zeiss Meditec, Clearside Biomedical, DelSiTech, DTx Pharma, Duet Therapeutics, Eyevensys, Galecto Biotech, Galimedix, Gemini Therapeutics, Glaukos, Innovent, iRenix, IvericBio, jCyte, Kanaph Therapeutics, Kanghong, Kodiak, LensGen, NGM Biopharmaceuticals, Inc., Novartis, Ocugenix, Oculis, Ocuphire, OcuTerra Therapeutics Inc., Omeros, Opthea, Oxurion, Palatin, Regeneron, RegenxBio, Retinal Sciences, Retrope, Roivant, Samsung Bioepis, Sandoz, Santen, Stealth Biotherapeutics, Sustained Nano Systems, Takeda, Théa, 2020 Onsite.

      Arshad Khanani, MD, MA, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Adverum, Allergan, Broadwing Bio, Chengdu, DORC, Genentech, Gyroscope, Gemini Therapeutics, lveric Bio. Kodiak, Nanoscope, Novartis, Opthea, Oxurion, Regenxbio, Roche, 4DMT, Surrozen Kanghong, Recens Medical. Grant/Research Support: Adverum, Allergan, Chengdu Kanghong, Genentech, Gyroscope, Gemini Therapeutics, Kodiak, Novartis, lveric Bio, Neurotech, Opthea, Oxurion, Recens Medical, Roche, Regenxbio. Speaker’s Bureau: Allergan, Genentech, and Novartis.

      Prithvi Mruthyunjaya, MD, MHS, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Alcon, and Castle Biosciences.

      Quong Dong Nguyen, MD, MSc, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Asciepix, Regeneron Pharmaceuticals, Rezolute, and Santen.  Grant/Research Support: Genentech, Gilead, Novartis, Regeneron Pharmaceuticals and Santen.

      Carl Regillo MD, FACS, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant:  Adverum, Alderya, Allergan, Annexon, Aviceda, Chengdu Kanghong,  Eyepoint, Genentech, Graybug, Iveric, Kodiac, Lineage, Merck, NGM, Notal, Novartis, Ocugen, Opthea, Stealth, Takeda, and Thea.  Grant/Research: Adverum, Allergan, Annexon, Astellis, Chengdu Kanghong, Eyepoint, Genentech, Graybug, Iveric, Kodiac, Lineage, NGM, Notal, Novartis, Opthea, Regeneron, and RegenXBio.

      Philip J. Rosenfeld, MD, PhD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Apellis, Bayer, Boehringer-lngelheim, Carl Zeiss Meditec, Chengdu Kanghong Biotech, Ocunexus (inflammX), Ocudyne, Regeneron, and Unity Biotechnology. Grant/Research Support: Carl Zeiss Meditec, lveric Bio., and Stealth BioTherapeutics. Stock/Shareholder: Apellis. Ocudyne. Valitor, and Verana Health.

      Stephen Smith, MD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Oncopeptides. Stock/Shareholder: iRenix Medical.

      Charles Wykoff, MD, PhD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant:  Adverum, Aerie Pharmaceuticals, Allergan, Allgenesis, Apellis, Arctic Vision, Arrowhead Pharmaceuticals, Bausch + Lomb, Bayer, Bionic Vision Technologies, Chengdu Kanghong Biotechnologies (KHB), Clearside Biomedical, EyePoint Pharmaceuticals, Genentech, Gyroscope, IVERIC Bio, Kato Pharmaceuticals, Kodiak Sciences, Long Bridge Medical, NGM Biopharmaceuticals, Novartis, OccuRx, Ocular Therapeutix, ONL Therapeutics, Opthea Limited, Oxurion, Palatin, PolyPhotonix, RecensMedical, Regeneron, RegenXBio, Roche, SAI MedPartners, Surrozen Takeda, and Verana Health. Grant/Research Support: Adverum, Aerie Pharmaceuticals, Aldeyra, Alimera Sciences, Allergan, Amgen, Apellis, Asclepix, Bayer, Boehringer Ingelheim, Chengdu Kanghong Biotechnology, Clearside Biomedical, Gemini, Genentech, Graybug Vision, Gyroscope, IONIS Pharmaceutical, iRENIX, IVERIC bio, Kodiak Sciences, LMRI, Neurotech Pharmaceuticals, NGM Biopharmaceuticals, Novartis, Oxurion, RecensMedical, Regeneron, RegenXBio, Roche, SamChunDang Pharm, Taiwan Liposome Company, Xbrane BioPharma.

       Paul Yang, MD, PhD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Adverum, AGTC, EcoR1, lveric Bio, Nanoscope Therapeutics, ProQR, TeamedOn, Vedere, and 4D.  Grant/Research Support: Acucela, AGTC, Biogen, Editas, FFB, lveric bio, ProQR, Reneuron, Sanofi, Spark, and 4D.

      EDITORIAL

      The Evolve staff and planners have no financial relationships with commercial interests. iVista staff and planners have no financial relationships with commercial interests. Nisha Mukherjee, MD, peer reviewer, has no financial relationships with commercial interests.

    • Disclaimer

      OFF-LABEL STATEMENT
      This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The opinions expressed in the educational activity are those of the faculty. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

      DISCLAIMER
      The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of Evolve, iVista Medical Education or Alcon Vision, Apellis, Carl Zeiss Meditec, Genentech, a member of the Roche Group. REGENXBIO and Regeneron Pharmaceuticals.

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